Cardiovascular Imaging for Clinical Practice by Stephen J. Nicholls, Stephen G. Worthley

By Stephen J. Nicholls, Stephen G. Worthley

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Nissen SE, Tardif JC, Nicholls SJ, Revkin JH, Shear CL, Duggan WT, Ruzyllo W, Bachinsky WB, Lasala GP, Tuzcu EM. Effect of torcetrapib on the progression of coronary atherosclerosis. N Engl J Med. Mar 29 2007;356(13):1304-1316. 84. Barter PJ, Caulfield M, Eriksson M, Grundy SM, Kastelein JJ, Komajda M, Lopez-Sendon J, Mosca L, Tardif JC, Waters DD, Shear CL, Revkin JH, Buhr KA, Fisher MR, Tall AR, Brewer B. Effects of torcetrapib in patients at high risk for coronary events. N Engl J Med. Nov 22 2007;357(21):2109-2122.

9 The cut off for an abnormal LVEF is < 55%; < 45% constitutes moderate dysfunction, and < 30% is severe LV dysfunction. Normal values for LV dimensions are based on the body surface area. 9cm/m2 representative of moderate to severe ventricular dilation. Other clinically useful assessments of chamber characteristics include right ventricular systolic function and right atrial enlargement for right-sided dysfunction, and left atrial enlargement (especially indexed to body size) for underlying LV diastolic dysfunction.

Population. 1 In the Western world, the most common causative factors for heart failure include myocardial ischemia, hypertension, or rhythm disturbances. Valvular heart disease is also a common cause of heart failure, particularly in the developing world because of the high prevalence of rheumatic heart disease. In many cases, the precise cause of heart failure may remain undetermined even with existing diagnostic modalities. According to the American College of Cardiology and American Heart Association (ACC/AHA) guideline, chronic heart failure is classified into four stages.

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