
By Mohamed Al-Rubeai; Martin Fussenegger
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PETCH and M. , and Zunino, F. (1998). Stimulation of the apoptotic response as a basis for the therapeutic synergism of lonidamine and cisplatin in combination in human tumour xenografts. Cancer 77, 434-439. , and Yuan, J. (2001). Identification of small-molecule inhibitors of interaction between the BH3 domain and Bcl-xL. Cell Biol. 3, 173-182. , Gonzalez, V. , Ellis, R. , and Nunez, G. (2000). CED-4 complex by EGL-1 is a critical step for programmed cell death in Caenorhabditis elegans. Chem.
2002). Role of vitamins in determining apoptosis and extent of suppression by bcl-2 during hybridoma cell culture. Apoptosis. 7, 231-239. , and Suzuki, E. (1995). Overexpression of bcl-2, apoptosis suppressing gene:: prolonged viable culture period of hybridoma and enhance antibody production. Biotechnology and Bioengineering 48, 118-122. , and Lemieux, R. (2002). Inducible expression of Bcl-XL restricts apoptosis resistance to the antibody secretion phase in hybridoma cultures. Bioeng. 79, 180-187.
Kastan, M. , Griffin, D. , Earnshaw, W. , Veliuona, M. , and Hardwick, J. M. (1998). Modulation of cell death by Bcl-XL through caspase interaction. A 95, 554559. Cockett, M. , Bebbington, C. , and Yarranton, G. T. (1990). High level expression of tissue inhibitor of metalloproteinases in Chinese hamster ovary cells using glutamine synthetase gene amplification. ) 8, 662-667. , and Borner, C. (2000). Bcl-2 is a monomeric protein: prevention of homodimerization by structural constraints. EMBO J.